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Food and Drug Administration, Center for Drug Evaluation and Research

Main findings: All Mediterranean diet patterns showed anti-inflammatory potential All showed favorable antioxidant profiles Extra-virgin olive oil supported a healthier lipid profile compared with coconut oil Diet quality mattered beyond calories and macronutrient composition Western-style dietary patterns showed a less favorable inflammatory and antioxidant profile, even when calories were comparable This study provides a guideline-informed framework for designing dietary interventions in MASLD research and highlights the potential of integrating dietary indices into future personalized nutrition tools