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Adolescents should be questioned about the chronic marijuana use to identify a condition termed cannabinoid hyperemesis syndrome (CHS) which is characterized by severe cyclical nausea, vomiting, and abdominal pain that are relieved by compulsive long hot water bathing (72)

Similarly, triptolide was implicated in the treatment of the breast cancer cell line MCF-7 through the induction of autophagy-mediated cell death by increasing ERK1/2 phosphorylation 43