22 May 2026 A Correction to this paper has been published: Abbreviations RA: Rheumatoid Arthritis GLP-1RAs: Glucagon-like peptide-1 receptor agonists GLP-1R: Glucagon-like peptide-1 receptor MNs: Microneedles FLS: Fibroblast-like synoviocytes HAMA: Hyaluronic Acid Methacrylate NPs: Nanoparticles mtDNA: mitochondrial DNA TNF-: Tumor necrosis factor- IL-1: Interleukin-1 IL-6: Interleukin-6 KEGG: Kyoto encyclopedia of genes and genomes GO: Gene ontology GSEA: Gene set enrichment analysis cGAS: Cyclic GMP-AMP synthase STING: Stimulator of interferon genes References Hemant S, Mukesh Kumar AD, Vaishali K, Deepak P, Ajeet SC, Dhiraj K, Rohit BS, Mukesh D
Those include Ozempic and its sister drug approved for obesity, Wegovy, which use semaglutide, and Mounjaro and Zepbound, for diabetes and obesity, respectively, which use the active ingredient tirzepatide
But when plant cells go to the gut, the bacteria there release enzymes to break down their cell walls. Their approach also avoids a step in the production of conventional GLP-1 receptor agoniststhe post-translational modifications, or chemical changes made to peptides after synthesis, required to make them functional
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