The 2017 Neelakantan paper in Biochemistry characterised a fluorescent assay for direct real-time monitoring of NNMT enzymatic activity, providing the analytical foundation for inhibitor screening including 5-Amino-1MQ (PMID 28121423)
Proper technique reduces risks like vein irritation, infection, or incorrect dosing
Footnotes Edited by: Ling Wang, Dalian Medical University, China Reviewed by: Nicola Alessio, University of Campania Luigi Vanvitelli, Italy Yesuf Adem Siraj, Bahir Dar University, Ethiopia Data availability statement The raw data supporting the conclusions of this article will be made available by the authors, without undue reservation
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