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Subsequent studies confirmed that liraglutide significantly improved PASI scores and histologic features of PsO, mainly epidermal thickness, inflammatory cell infiltration, and keratinocyte hyperproliferation (42, 55)

Formulation can improve both stability and absorption, but even with the most advanced formulation, the only oral GLP-1 available today achieves roughly one percent absorption, and uptake varies widely between patients, making consistent dosing a challenge

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Pharm Res 30(5):14471457 Madsbad S (2016) Review of head-to-head comparisons of glucagon-like peptide-1 receptor agonists