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The standout finding is not just the magnitude of weight loss, but the concurrent improvement in knee osteoarthritis pain and function, says Daniel Ghiyam MD, a California-based physician specializing in hormone optimization, metabolic health and preventive care

Although UA transporters are found in many cells and organs, they are mostly concentrated in kidney and intestine, i.e., in the organs with a key role in UA excretion and regulation of UA concentration in the body

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This function is essential for energy metabolism, particularly during physical activity or periods of increased energy demand