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Glutathione S-transferases (GSTs) are the enzymes expressed in the cytosol, microsomes, and mitochondria and catalyze glutathione conjugation to electrophilic compounds, not only produced from exogenous xenobiotics by biotransformation but also arise from endogenous substances

The medication is generally well-tolerated, with the most common side effects including nausea, vomiting, diarrhea, abdominal pain, constipation, heartburn, and burping

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