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Using single-cell transcriptional profiling of kidney tissue from youth with type 2 diabetes (T2D) who showed minimal clinical evidence of DKD, we identified cell type enrichment of HIF-regulated genes, findings that replicated in people with later-stage DKD in the Kidney Precision Medicine Project (KPMP)

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This article is about the other side of the conversation.) The Safety Profile: What Clinical Studies Show Let's start with the reassuring part