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The American Diabetes Association Standards of Care and American Association of Clinical Endocrinology guidelines for obesity management acknowledge that patients with depression or anxiety can be candidates for pharmacological weight loss interventions, provided their mental health condition is adequately controlled

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Premature depletion of ovarian reserve leads to an early cessation of ovulation and subsequent infertilityevents that are intricately associated with the activation of PCD pathways (Marcozzi et al., 2018)