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Sensibilizadores a la insulina en el tratamiento del sndrome de ovario poliqustico Los sensibilizadores a la insulina ganan relevancia al incidir en la etiologa del SOP, reduciendo la RI, normalizando el metabolismo de la glucosa y disminuyendo las concentraciones de andrgenos, mejorando la tasa de ovulacin 5 , 41 - 48

It says patients with concurrent autoimmune conditions, thyroid surgery within the past three months, or unstable TSH levels should defer GLP-1 initiation until metabolic stability is confirmed

The direct endocrine consequence of the gonadal dysgenesis is hypergonadotropic hypogonadism, and the lack of testosterone negatively affect the normal pubertal spurt