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While this matters less for weekly formulations than it would for daily ones, it still disrupts the predictability of your side effect and appetite suppression patterns

Sitagliptin binds to the DPP-4 enzyme, preventing the breakdown of glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)

Cardiovascular benefits have been demonstrated specifically for dulaglutide in the REWIND trial, showing that the medication can reduce major adverse cardiovascular events in adults with type 2 diabetes who have established cardiovascular disease or multiple cardiovascular risk factors