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Quality assessment and critical appraisal for the systematic review of the included studies The methodological quality of the included studies was evaluated independently by two reviewers using the Study Quality Assessment Tools developed by the National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health (NIH), tailored to the design of each included study

Future availability will depend on the outcome of ongoing clinical trials and regulatory review by the Medicines and Healthcare products Regulatory Agency (MHRA)

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PCOS and Insulin Resistance Polycystic ovary syndrome affects 6-12% of Canadian women of reproductive age