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2.14 Differential scanning calorimetry (DSC) Being a tool that provides a thermodynamic profile of protein unfolding/denaturation process by measuring the heat absorbed or released by a protein sample as its temperature is changed, differential scanning calorimetry (DSC) is different from the biophysical technique discussed so far, all of which provide information on some structural features of a protein, such as its secondary structure, flexibility, hydrodynamic dimensions, or solvent/protease accessibility

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This can happen because of past surgeries that changed the intestinal shape like gastric bypass and bowel resections, diverticula or small pouches in the intestine and intestinal kinking or narrowing from chronic inflammation or scar tissue