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This occurs because heat increases the kinetic energy and causes the molecules to vibrate so rapidly and violently that the bonds are disrupted

Jesse Rowley and his colleagues from Utah, have attacked this problem for variants in the ITGA2B and ITGB3 genes in patients with Glanzmann thrombasthenia (GT) by adopting CRISP-Cas-mediated homology-directed repair (HDR) to reproducibly insert precise gene variants into human cord blood and adult CD34+ cell-derived megakaryocytes (MKs)