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For example, a meta-analysis revealed the following changes when comparing GLP-1 agonists to placebo: Waist circumference dropped by 5.16 cm BMI decreased by 2.42 kg/m Triglycerides were reduced by 0.20 mmol/L Total testosterone levels fell by 1.33 ng/mL The reduction in waist circumference is particularly impactful because visceral fat is metabolically active and worsens insulin resistance

Shauna Levy, a specialist in obesity medicine and the medical director of the Tulane Bariatric Center in New Orleans, referring to the class of drugs that include Wegovy and Zepbound