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In this context, vitamin supplementation beyond industry standard did not provide any consistent advantage over supplementation at NRC 2012 standards, which are below what is normally fed

It disrupts the balance of the tumor immune microenvironment by synergistically regulating immune cells, precisely antioxidant, and relieving immune suppression, forming a microenvironment conducive to anti-tumor immunity, thereby exerting a powerful cancer immunotherapy effect and showing good biocompatibility and tumor accumulation characteristics [427, 428]

Ethics declarations Ethics approval and consent to participate The Ethics Committee of The Third Hospital of Qinhuangdao approved all experimental protocols