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Gut barrier disruption patterns EHS-induced gut barrier dysfunction is primarily driven by splanchnic hypoperfusion (from increased skeletal muscle blood flow during exertion) and mechanical stress (muscle contraction), leading to rapid translocation of LPS and bacteria within 24 hours [61]

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Saberian C, Amaria RN, Najjar AM, Radvanyi LG, Haymaker CL, Forget MA, Bassett RL, Faria SC, Glitza IC, Alvarez E, Parshottam S, Prieto V, Lize G, Wong MK, McQuade JL, Diab A, Yee C, Tawbi HA, Patel S, Shpall EJ, Davies MA , Hwu P, Bernatchez C

In the Control group, normal ovarian morphology was observed, with well-preserved primordial (yellow arrowhead), primary, secondary, and Graafian follicles