Other serious side effects that require medical attention include unexplainable muscle pain, muscle tenderness or weakness, dark brown urine (indicative of Rhabdomyolysis), increased levels of calcium (symptoms may include increased thirst, frequent urination, nausea, vomiting, constipation, pain in bones, confusion, and fatigue), high blood pressure (manifested as headache, dizziness, vision problems, and shortness of breath), palpitations, decreased blood platelet count (evidenced by bleeding or bruising, fatigue, and weakness), anemia symptoms such as fatigue, loss of energy, weakness, and shortness of breath, bronchitis symptoms like coughing and difficulty breathing, low blood sugar, seizures, and dermatitis exfoliative symptoms such as rashes, redness, widespread blistering, or peeling of the skin and mucosa (mouth)

have reported: Gastroparesis (stomach paralysis) Severe abdominal pain Pancreatic cancer Gallbladder disease (including surgical removal) Intestinal obstruction or blockage Life-threatening dehydration or malnutrition Many of these conditions require hospitalization, invasive procedures, or long-term medical care
For people with type 2 diabetes, the promise of retatrutide lies in combining deep weight loss with meaningful improvements in blood sugar
Employers should stay informed about these regulatory changes to manage prescription drug costs and ensure employee medication access