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Data availability Supporting computational and chemical methods (including compound synthesis and NMR spectra) are described in the supplementary file, which also includes Supplementary molecular modeling results, supplementary tables, figures, movies, PDB-formatted files

Glutathione works mainly in two ways: 1

G6PD-d may consequently hinder activation, differentiation, proliferation and the expansion of Th1 and CD8 + T cells during acute stimulation 89,118,119

If these widely available drugs could be repurposed to protect the brain, it could offer a much more scalable and affordable alternative for millions of families in the U.S. Previous research in cell lines and animal models found the medications can reduce brain inflammation, improve how the brain uses insulin and help brain cells communicate better with one another