is depression a side effect of glp 1 GLP-1RA Essentials in Gastroenterology: Management, Precautions for Endoscopy and Applications for Gastrointestinal Disease Treatment GLP-1 Drugs and Weight Loss:

The estimated mean weight loss was 7.03 kg in the placebo group, 11.19 kg in the exercise group, 13.74 kg in the liraglutide group, and 16.88 kg in the combination group

Importante destacar que existe un circuito disociado en el tronco enceflico entre saciedad y aversin: mientras la activacin del NTS induce prdida de apetito sin efectos adversos, la del rea postrema puede generar nuseas, explicando los efectos secundarios gastrointestinales que presentan hasta un 40% de los pacientes con GLP-1RA

The Biochemical journal

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