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Olpasiran and lepodisiran are GalNAc conjugates containing siRNAs that target the LPA gene, promoting RISC-mediated degradation of Apo(a) mRNA and preventing Lp(a) particle assembly in hepatocytes

The value of raising it early is that a provider can set up monitoring from the beginning rather than reacting to a missed period months later

doi:10.3390/nu8110748 119

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