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Underexplored peptides that activate multiple receptors or signaling cascades may therefore be particularly well suited to modern therapeutic strategies that embrace controlled polypharmacology

More broadly, there are certain situations in which you should seek prompt medical advice, regardless of whether you are on an investigational medication: Symptoms of a UTI that do not improve within 48 hours contact your GP or use NHS 111 Fever (38C or above), rigors (shivering), or back/flank pain these may indicate a kidney infection (pyelonephritis) and warrant same-day medical assessment

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& Zdravkovic, M