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Hubermans logic that angiogenesis promoters should be avoided due to their potential cancer risks, it would imply that antioxidants like vitamins C, E, NAC, and B12 pose serious dangers due to their potent angiogenic effects

In cancer cells, increased lactate concentrations have been reported to suppress apoptosis through HIF-1-mediated upregulation of anti-apoptotic proteins, including BCL-2 and survivin, while concurrently promoting ferroptosis resistance via SCD1 upregulation (58,141)

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The American Academy of Pediatrics and the American Diabetes Association have both recently recommended screening for abnormalities in glucose metabolism in children with a body mass index (BMI) at or above the 95th percentile [21,22]