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Enterohepatic circulation further influences LT4 metabolism, with conjugation via glucuronidation and sulfation in the liver, secretion into bile, and partial reabsorption by the intestinal flora (Eghtedari And Correa 2023)

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In WADA FAQs on the Prohibited List they note, "Use of supplement products that have been subjected to one of the available quality assurance schemes can help to reduce, but not eliminate, the risk of an inadvertent doping infringement." WADA does not approve, certify, or endorse dietary supplements

25 Mechanistically, LCA targets the protein TULP3 to activate the sirtuin-v-ATPase-AMPK signaling axis, thereby exerting antiaging effects through conserved metabolic regulatory pathways