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The psychosocial impact is further compounded by the frequent misdiagnosis or underdiagnosis of the condition, which can delay appropriate care.27 Several studies have demonstrated that the quality of life in patients with lipedema is markedly reduced compared to age-matched controls.15,17,28 Some of the tools used included assessments of symptom severity, quality of life, satisfaction with life, psychological flexibility, and social connectedness

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Most people feel the worst of it in the first few weeks and after each dose bump

Dermatology Research and Practice