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However, their cytotoxicity limited their application in nanoparticle design

In contrast, SIRT3 deacetylates and activates PDHA1 acetylation, linking glycolysis and OXPHOS

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LDL Isolation and Characterization : Oxidation Inhibition Assay : Oxidation Product Quantification : Calculate percentage inhibition of LDL oxidation using the formula: % Inhibition = [1 - (Treatment - Native) / (Oxidized Control - Native)] 100 where "Native" represents non-oxidized LDL, "Oxidized Control" represents vehicle-treated oxidized LDL, and "Treatment" represents this compound-treated oxidized LDL