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3, Oncogenic PI3K/AKT signaling stabilizes and activates nuclear factor erythroid 2related factor 2 (NRF2), a key regulator of antioxidant genes, driving upregulation of GSH biosynthetic enzymes

A medical provider can help determine if a patient would benefit from these other medications and discuss risks versus benefits with the patient

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(1) Limitations of Use: Janumet Dosage and Administration Take JANUMET orally twice daily with meals