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GLP-1(7-36), produced through the proteolytic processing of proglucagon and released by L cells in the small intestine and colon, is rapidly degraded by dipeptidyl peptidase 4 with a half-life of approximately 2 minutes

Nevertheless, results from our study clearly suggest that GSH-mediated biofilm disruption is negligible at neutral pH, and thus the acidity of GSH is a critical factor in the effectiveness of its biofilm disruption and reduction of bacterial viability

Does the drug produce the intended downstream effects in healthy individuals or the specific patient population being targeted