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Description

The combination drug bupropion/naltrexone activates pro-opiomelanocortin (POMC) neurons, releasing alpha-melanocyte-stimulating hormone, providing positive effects on body weight regulation [37]

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Consistently, TRPV1 is also found to be expressed by the murine enteroendocrine cell line model STC-1 and its agonism induces the release of GLP-1 in vivo (377)

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