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Obesity, hypertension and insulin resistance

Data availability The data generated in this study are provided in the Source Data file which can be accessed here: The raw MRS data can also be accessed using the same link, including the simulated basis set that was used during the data analysis

Regarding the underlying mechanism, IR in the brain significantly contributes to neurodegenerative processes, and GLP-1RAs modulate downstream signaling pathways, including mitochondrial biogenesis, autophagy, inflammation, and cell survival

Although IL-10 is typically associated with anti-inflammatory properties, its coexistence with pro-fibrotic markers such as TGF- and IL-13 implies a complex interaction in which inflammation and fibrosis may manifest simultaneously (Farr et al