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SIRT1, localized in the nucleus, deacetylases and activates proliferator-activated receptor gamma coactivator-1 (PGC-1), which leads to increased mitochondrial biogenesis 103

In many cases, tapering slowly may help the body adjust better and reduce the shock of increased hunger

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Nutr Metab Cardiovasc Dis 29(11):11511167 Montjean D, Entezami F, Lichtblau I, Belloc S, Gurgan T, Menezo Y (2012) Carnitine content in the follicular fluid and expression of the enzymes involved in beta oxidation in oocytes and cumulus cells