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The sites are reported to be formed by a high-affinity multinuclear iron cluster in which redox-inactive Fe 3+ is bound by oxo and/or hydroxo bridges and is surrounded by catechol groups of NM, and a lower affinity mononuclear iron site in which a single iron ion is six-coordinated by oxygen atoms of catechol moieties, and possibly by water or hydroxo groups (Zecca et al

PRP therapy uses the patients own blood, which eliminates the risk of allergic reaction or disease transmission

Long-term human safety data are not yet established

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