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This means retatrutide does not rely solely on appetite suppression

Patients should ask their Defy Medical provider directly whether an in-person evaluation is required under current rules before initiating a controlled-substance prescription

Week 34 Many patients notice: Enhanced brightness Reduction in dullness More even complexion Week 58 Visible improvements often become more apparent: Better skin clarity Reduction in tanning Improved radiance Month 23 Most patients experience: Noticeable brightening Improved skin quality Better pigmentation control Month 36 Peak results may become evident with continued treatment and maintenance

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