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Side Effect How Common Typically When Usually Resolves Nausea Very common First 14 weeks / dose increases Within a few weeks Diarrhoea Very common Early treatment Within a few weeks Constipation Very common Throughout treatment With hydration and fibre Reduced appetite Very common Throughout treatment Ongoing (intended effect) Vomiting Common Early treatment / dose increases Within a few weeks Fatigue / tiredness Common Early treatment / dose increases Usually within 12 weeks Dizziness Common Early treatment Usually temporary Abdominal discomfort Common Early treatment Within a few weeks Injection site reactions Common After injecting Usually within hours Headache Less common Early treatment Usually temporary Hair thinning Less common Sustained rapid weight loss Often resolves over time Pancreatitis (rare) Rare Any stage Requires immediate review A note of reassurance: The vast majority of Mounjaro side effects are mild, temporary, and manageable

Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways

Have thyroid disorders (some formulations include ingredients affecting thyroid)