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The Graves IgGs or TSIs bind to the TSH receptor and cause the permanent stimulation of thyroid glands that result in the overproduction of thyroid hormones

Shewale JB, Mitchell KG, Nelson DB, Conley AP, Rice DC, Antonoff MB, Hofstetter WL, Walsh GL, Swisher SG , Roth JA, Mehran RJ, Vaporciyan AA, Weissferdt A, Sepesi B

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