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[10] [16] The most frequent side-effects of tirzepatide include nausea, vomiting, diarrhea, decreased appetite, constipation, upper abdominal discomfort, and abdominal pain

The findings compiled in this table directly inform Section 9 (Discussion) in three key areas: regarding clinical significance, it supports the prioritization of stratified interventions based on nutrients with strong evidence (e.g., dietary fiber and EPA/DHA), particularly for inflammatory depression subtypes (65, 124)

In various healthcare settings, acute kidney disease (AKD) has seen a rising incidence 4,5 , with associated heightened risks of all-cause mortality, end-stage kidney disease, and chronic kidney disease (CKD) 6