Key points Metabolomic profiling in patients with systemic lupus erythematosus (SLE) has revealed substantial alterations in amino acid, lipid and energy metabolism, especially linked to oxidative stress and mitochondrial dysfunction, providing valuable indicators of disease activity and severity
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Behavioural and Emotional Regulation: Challenging behaviours such as meltdowns, self-injurious behaviour, aggression or extreme rigidity are often the result of unmet communication needs, sensory overload, anxiety, or an inability to regulate overwhelming emotions
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