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Basal endothelial glycocalyxs response to shear stress: a review of structure, function, and clinical implications

Previous research results supported that activation of GPX4 contributes to the suppression of inflammation (Meng et al., 2015)

Mechanistically, BCAT2 as the key enzyme mediating the metabolism of sulfur amino acid, regulated intracellular glutamate level, whose activation by ectopic expression specifically antagonize System X c inhibition and protected liver and pancreatic cancer cells from ferroptosis inducers (erastin, sorafenib, and SAS)-induced ferroptosis in vitro and in vivo (Wang K