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Who should be cautious Again, not medical advice, but caution is reasonable if you have: Known copper overload concerns or unexplained high copper patterns on prior testing Significant liver dysfunction (copper handling can be affected) Complex chronic inflammatory conditions where adding new immune active compounds tends to flare symptoms A history of reacting strongly to supplements or peptides Also, pregnancy and breastfeeding is generally not the time to experiment with longevity peptides

[PubMed] Challa, F., Getahun, T., Sileshi, M., Nigassie, B., Geto, Z., Ashibire, G., Gelibo, T., Teferra, S., Seifu, D., Sitotaw, Y., Bekele, A., Abate, E., & Baye, K