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Nirala Jacobi: So it's really good that we have some way of tracking some of this because I think you're absolutely right

Although some individuals have difficulties in adherence, the majority of studies show similar dropout or non-adherence rates in the treatment and control groups

Gastrointestinal effects are particularly common, especially during treatment initiation and dose escalation: Nausea classified as 'very common' (affecting more than 1 in 10 patients) in the SmPC [1] [2] Vomiting 'common' (affecting up to 1 in 10 patients) Diarrhoea 'common' according to the MHRA/EMC SmPC Constipation 'common', likely related to delayed gastric emptying Abdominal pain or discomfort 'common', generally mild to moderate in severity Decreased appetite 'common', which may lead to reduced food intake and weight loss (note that while weight loss can occur with Ozempic, it is not licensed for weight management in the UK) [1] [2] These gastrointestinal symptoms usually diminish over time as the body adapts to the medication

Without enough B12, people may experience fatigue, brain fog, or even nerve-related issues