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Our results are consistent with a post hoc analysis of the EXCEL trial [29] which concluded that exenatide combined with SGLT-2i reduced the risk of MACE (defined as cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke) compared with exenatide monotherapy and also improved eGFR significantly

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The cells were collected by centrifugation at 2000 g for 5 min and washed in phosphate buffered saline