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While both tirzepatide and semaglutide reduced appetite, tirzepatide's superior weight loss outcomes suggest that other mechanisms, including increased energy expenditure, also play a role

None of these compounds is an approved therapy for anything, and no blend has an approved indication

The approach to the resistant prolactinoma includes escalation to maximally tolerated cabergoline dose and if necessary complementary approaches such as pituitary surgery, radiotherapy, and drugs such as temozolomide (81)

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