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Histopathological examination revealed partial restoration of liver, kidney, and pancreatic integrity, accompanied by reduced malondialdehyde and elevated superoxide dismutase activity

doi:10.1097/MD.0b013e3181ca4290 12Ye LP, Zhang C, Zhu QX

Six weeks of hypoxic treadmill exercise significantly increases Sirt3 expression in the skeletal muscle of C57BL/6J mice, followed by upregulating the levels of FOXO3a, SOD2, PINK1, and Parkin proteins, with no significant change in the expression of Drp1 proteins, which promotes the level of mitophagy, and consequently improves the synthesis of ATP and the activity of citrate synthase (CS) in the skeletal muscles and increases mitochondrial volume and number

KP: Resources, Writing review & editing, Writing original draft