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They found that people taking semaglutide (Ozempic) or tirzepatide versions of GLP-1 drugs were twice as likely to develop NAION (non-arteritic anterior ischemic optic neuropathy)
These observations underscore the profoundly context-dependent and pathway-specific nature of mitophagy in PDAC, highlighting its potential as a therapeutic target for combination therapy
Measurements of intracellular Ca 2+ have also frequently been used to assess GLP1 receptor biased agonism in heterologous cell systems
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