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Signs of skin cancer on the leg may include: Dry, scaly patches that are reddish or pink in color Small, raised bumps that can range from pearly translucent to red Growths with raised edges Open sores that refuse to heal and may either bleed or puss Dark spots with uneven borders A mole or spot on the thigh, shin, or knee that evolves over time Use the ABCDEs At home, you can complete a self-exam using the ABCDEs of skin cancer

As the saying goes, the hardest part is starting

doi: 10.2106/JBJS.CC.17.00133

Free Radic Biol Med 63:187194 Sanacora G, Mason GF, Rothman DL et al (2002) Increased occipital cortex GABA concentrations in depressed patients after therapy with selective serotonin reuptake inhibitors