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While Dihexa-specific desensitization kinetics havent been comprehensively characterized, research on HGF and c-Met receptor signaling in other contexts indicates receptor downregulation begins within 24-48 hours of sustained agonist exposure, with maximum internalization occurring around 72 hours

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SAC regulates the Keap1/Nrf2/GPX4 signaling pathway to inhibit Ferroptosis Iron-mediated lipid peroxidation constitutes the central process of ferroptosis

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