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Serious but rare risks include pancreatitis, gallbladder events, and a thyroid C-cell tumor boxed warning from rodent studies

Hopefully this will mean more collaborative trials between rheumatologists and cardiologists, and continued emphasis on diet and exercise for patients who have inflammation secondary to obesity

In a study with 26 subjects, who were mainly overweight but with normal glucose tolerance, there was an increase in serum calcitonin levels after a 75-g oral glucose tolerance test which correlated with insulin levels, suggesting a possible relationship between insulin and calcitonin (88)

It is available for research purposes and used off-label in some clinical settings