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Topical application is limited by the stratum corneum barrier, with near-zero penetration through intact skin (Li et al., 2015)
Glutathione depletion activates mitogen-activated protein kinase (MAPK) pathways that display organ-specific responses and brain protection in mice
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By forming Peptibodies through conjugation with antibodies, the tree blooming effect can be achieved, leveraging the longer half-life of antibodies to enhance the stability of peptides
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