Other downregulated transcripts included membralin isoform X1, leucine-rich repeat neuronal protein 1, and abnormal spindle-like microcephaly-associated protein isoform X1
Same number of units, different concentration, completely different dose
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Curcumin-supplemented KI mice showed reduced mHTT aggregation and upregulated mRNA expression of striatal DARPP-32 and dopamine receptor D1, which were accompanied by behavioral recovery, particularly in rearing deficits (Hickey et al., 2012)