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Los pacientes fueron aleatorizados para seguir un ciclo teraputico durante un perodo total de ocho aos: citicolina (1,000 mg/da, por inyeccin intramuscular) o placebo (solo -bloqueadores) durante un perodo de dos meses seguido de un perodo de lavado de cuatro meses (87)

Dedicated urate-lowering therapy (such as allopurinol or febuxostat) remains the mainstay of treatment for patients requiring pharmacological management of hyperuricaemia, in line with NICE guidance on gout management

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This can make it easier to build consistent habits around meals, hydration, and balanced nutrition